Bible believers and quran believers actually do point at their books and claim they are proof of their religion. No spider-man (there, I added the hyphen for you) reader, religious or not, big comic nerd or not, would ever say the comic is proof of spider-man’s existence because of course that’s ridiculous. So adding spider-man to this meme does make a lot of sense - putting them in contrast, hoping to make people understand how illogical it is to treat certain man made works of fiction so completely differently than others.