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Cake day: June 6th, 2023

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  • IrritableOcelot@beehaw.orgtoScience Memes@mander.xyzIt hurts me.
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    7 days ago

    Yep! The LD50 is 12.5% in air (higher than I thought, honestly) and yes the issue is that it binds preferentially to hemoglobin.

    The main treatment for sub-lethal exposure is just supplying pure oxygen to kick the equilibrium the other way and slowly remove the CO from your system. It won’t all come off, but your body recycles red blood cells pretty quickly, so you’re back on your feet within a few hours and back to normal within a few days. However, there’s no treatment for lethal doses, people have proposed using things like cobalt porphyrins (which bind CO even better than iron hemes) to more quickly sequester the CO from your hemoglobin, but that’s not been trialled yet in humans.

    I wasnt aware of its use as a neurotransmitter (but I’m absolutely going to look into it now), but its barely soluble in water so there must be more going on there. just like urea, it’s a natural waste product, and typically one your body wants to get rid of reasonably quickly.

    Edit: from a chemical perspective, NO and CO “look” electronically similar to a NO-binding protein, so I expect most of these effects of CO are actually just it activating pathways natively activated by NO.





  • When you’re supposed to choose between siding with the Mages and Templar, it tells you to go back to the war room, which I assume should activate some kind of cutscene…but nothing happens. You just get to choose more missions on the map. I can’t tell how far back it bugged out, even if I go back to before starting that questline, I get the same issue.

    From the steam forums, it seems like this has been a known bug since at least the original steam release :/





  • Would I have to use flowers that are closer to cyan, magenta, and yellow so it is closer to the cmyk color model or does that not help?

    The thing about that is the “k” in CMYK is black, because it’s very hard to mix other colors to get anywhere close to black. I think you’d want to look for a pigment which is black and bleaches under UV, but that’s going to be hard, since bleaching from black fully to white so other colors can be applied will be crazy hard. Might want to just compromise to brown being your “black point”.

    Do I need to do it in multiple layers?

    Yes. Most of these pigments are only going to be sensitive to UV light, so each layer is going to be a monochrome representation of the total light exposed on that layer.

    Also I was planning on trying to use the paper as a replacement for photo paper in pinhole photography with it instead of a mask.

    That makes this almost impossible, frankly. The mask method means that you have direct sunlight hitting the paper at full intensity. For a pinhole camera, for one thing you’re not pointing at the sun, so the light is maybe 5-10% as intense, but the pinhole aperture dictates the amount of light. Say the paper is A4 for math’s sake, and so is 62,370 mm^2. A typical pinhole camera’s pinhole is probably a bit less than 1mm^2, but let’s say it’s 1.

    The brightness of light on the pinhole is the same as it would be on a piece of paper held in the same place, but then once inside the camera the light spreads out to cover the whole paper. That means that relative to the mask method and leaving it in the sun, the pinhole method exposes the anthrotype to 0.05×1/6,2370 = 0.0000008 the light of the mask method. This is all too approximate to calculate what the exposure time might be, but it’s unreasonably long, a couple hundred years.

    I think the most practical method would be to take a digital photo, filter the colors into a monochrome for each dye you want to use, print that on a transparency, and use that as a mask.


  • Hmmm interesting idea!

    I think your biggest limitations are going to be contrast and exposure bleed. First of all, typically mixing dyes of different colors (especially plant pigments which are not likely to be super dense), you get brown rather than black. For contrast, I think you’d be limited again by the lack of color density in your pigments, but as long as you’re OK with pastel colors, that could work.

    For exposure, at least based on the Wikipedia page you linked, you’re talking one layer taking a 2h exposure. Trying to do say three layers would then take six hours, so whatever you’re using as a mask has to be super absorbent or reflective to UV (think very thick black paper or tinfoil). Anything else, and your underlying layers are going to bleach somewhat.


  • I actually use GIMP regularly these days, I found Scribus harder. Yes, Inkscape is more friendly. It doesnt follow the Adobe paradigm, but it’s pretty quick to learn and is closer to the Adobe layout than other software.

    The only thing that’s kinda funky in Inkscape is cropping, which is done via “clipping”, using another polygon to mask the component below. The selectable image stays the same size (but mostly invisible), making automatic alignment kinda annoying. However, thats for bitmap images, and Inkscape is meant to be vector-first, so that’s not the end of the world.



  • In chemistry a lot of the foundational synthesis and work is as old as the 60s and 70s; people build on it, but in some cases those early papers said pretty much all there is to be said on a topic, so there’s no reason to republish on it.

    I’ve had to cite papers as old as the late 30s before, because no one has ever found anything to fix or correct about their work! Pretty impressive if you ask me, given how few tools they had.