Server side anti cheat can’t distinguish good players from aimbots.
Neither can a rootkit, which should be unconditionally illegal and send CEOs to jail for putting in their product. There are no exceptions and no scenarios where it can possibly be acceptable for a video game to access any operating system anywhere near that level. Every individual case should constitute felony hacking, with no possibility of “user consent” being a defense even if they do actually clearly and explicitly ask for “permission”.
If you don’t physically control the hardware, it is not secure.
The only valid approach to preventing cheating that matters is to have authoritative servers. Nothing else works, nothing else theoretically can work, and nothing else can possibly be described as anything but malware. There is literally no possible scenario where any entertainment company knowing anything about what else is happening on your computer can be justified.