• retrieval4558@mander.xyz
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    10 months ago

    Agree. I work in an ICU and see the effects of alcohol and tobacco CONSTANTLY. I’ve seen a serious problem from cannabis once.

          • LinkOpensChest.wav@lemmy.one
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            10 months ago

            Bad take, considering how helpful cannabis can be to those who use it, how little evidence there is to show that it drastically increases one’s risk of heart disease, and how many substances we consume with far worse side effects (e.g., SSRIs, aspirin, acetaminophen, etc.)

            On the other hand, alcohol has no benefits when taken internally.

            • phoneymouse@lemmy.world
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              10 months ago

              Still too early to really say for sure. You don’t really know yourself and you aren’t citing any studies.

              • LinkOpensChest.wav@lemmy.one
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                10 months ago

                I’ll provide the full works cited once I finish my paper. Atm I’m just commenting in a shitpost community.

                I do feel confident I’m right, though. Cannabis has known benefits for certain conditions, which is why you can get a prescription.

                As for you, I hope you don’t drink caffeine, which is far more addictive and harmful than THC.

                  • LinkOpensChest.wav@lemmy.one
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                    10 months ago

                    Anxiety, insomnia, hypertension, mood swings, urinary incontinence, diarrhea, dehydration, irregular heartbeat, overdose and death at very high doses

                    Not to worry, though. As scary as these effects may sound, for the vast majority of people, caffeine is generally considered as safe as other soft drugs such as aspirin or cannabis.

      • Styxia@lemmy.world
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        10 months ago

        From the health.com link that references this article includes edibles as a risk vector.

        Previous studies have suggested that tetrahydrocannabinol (THC), the molecule responsible for the psychoactive effects of cannabis, acts on receptors that are found in the central nervous system and in the heart and blood vessels. This interaction between THC and blood vessels may provide a pathway for cannabis to promote inflammation and the buildup of plaque, ultimately leading to CAD. The same effects would not necessarily be expected with the use of cannabidiol (CBD), another active ingredient in cannabis and hemp that is commonly extracted for products that do not contain THC.

        So you are indeed correct. To a point. The ICU observation doesn’t minimize the risks of cannabis but provides a perspective on the prevalence of the issue, and the tone in your responses is likely behind the downvotes you are lamenting.

        Regardless, thank you for sharing the links, they were helpful.

      • retrieval4558@mander.xyz
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        10 months ago

        It’s very possible we haven’t learned to recognize them. (although that fact also implies that the effects are subtle, doesn’t it?)

        Thank you for the links. I didn’t have time to review them all in detail but I did take the time to find the study that Forbes was referring to ( because a sample size that big is very interesting, even if it was just a population study.

        Their inclusion criteria were people who had Cannabis Use Disorder documented on their chart compared to statistically matched people who did not. They tried to control for socioeconomic factors.

        In my opinion, it’s worth noting that people who end up with that chart diagnosis are going to be on the heavier end of users, as the majority of people who use pot don’t report it to their doctors nor end up in the EDs with cannabis related complaints.

        In comparing the two populations, they found that the ABSOLUTE RISK (not relative risk) of adverse cardiovascular events was increased by 0.9%. Notable limitations to the study include that they don’t know exactly how much cannabis each person was using, they couldn’t fully control for tobacco use, and (imo) the exclusion of people with previous cardiovascular events was limited to a 2 year lookback, which may be a bit limiting.

        So the conclusions we can draw from this is “within a population of the heaviest cannabis users with greater than average healthcare exposure, risk of CVD goes up by less than a percent.”

        I’m totally willing to believe that it presents some risk- I just think it’s more likely to be even less of a factor (or at least in the same ballpark) in the development of CVD than things like diet and exercise.

        Comparing this study to some established numbers on tobacco can be helpful here. A quick search on the medical database UpToDate showed me some data suggesting that in heavy smokers, the risk of CVD was 600% greater (relative risk), which is 10 times higher than the 60% relative risk increase that we saw in the cannabis study.

        https://doi.org/10.1111/add.16337 cannabis study https://pubmed.ncbi.nlm.nih.gov/8565161/ tobacco study

        • RubberElectrons@lemmy.ml
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          10 months ago

          This is great, thanks for the info.

          I’m not changing my opinion on my stance, but it’s nice to see other people genuinely interested in the conversation.